What can Frizzled7 reveal about breast cancer development?
A new study shows that Frizzled7, a protein present on human breast epithelial cells and a component of the Wnt signaling pathway is uniquely controlled by the Notch signaling pathway, both of which play key roles in mammary gland formation and breast cancer development. Evidence supporting the potential ability to regulate Notch-mediated Wnt signaling by targeting the NOTCH3-FZD7signaling network is presented in the study published in Stem Cells and Development.
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