Scientists found new way to synthesize chiral tetraarylmethanes

A group of scientists at the Hong Kong University of Science and Technology (HKUST) have achieved a catalytic asymmetric synthesis of tetraarylmethanes by chiral phosphoric catalysis. With this process, two libraries of structurally distinct CTAMs were efficiently synthesized with high enantioselectivity. Preliminary biological activity study indicated that these spherical molecules are highly promising anticancer agents.
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