Hip implants — metal wear impairs bone-forming cells' function

In metal-on-metal pairings, both the shell and head of an implant consist of a cobalt-chromium-molybdenum alloy. The release of metal ions into the body has been reported as a result of implant wear. Bone loss (osteolysis) was observed in many cases. Recently, researchers from Charité — Universitätsmedizin Berlin and DRK Klinikum Westend have been able to show that cobalt and chromium release contributes to bone loss. Their findings have been published in the journal Biomaterials.
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